Dermorphin
Original price was: $149.99.$120.99Current price is: $120.99.
In stock
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99.7% — exceeds 99.00% minimum spec
- Batch
- DR-202607-001
- Test date
- July 23, 2026
- Method
- HPLC + MS
- Lab
-
Bioviridian
College Station, TX
Description
Dermorphin peptide Details
Dermorphin is a naturally occurring heptapeptide first isolated from the skin secretions of South American frogs of the genus Phyllomedusa, notable in the pharmacology literature for its exceptionally high binding affinity and selectivity for the mu-opioid receptor — reported in some studies to exceed that of morphine by several orders of magnitude. This potency and receptor selectivity has made dermorphin a valuable research tool for studying mu-opioid receptor pharmacology and structure-activity relationships, independent of any therapeutic application. Because dermorphin is a peptide (rather than an alkaloid opioid), it does not cross the blood-brain barrier efficiently via typical routes, which has driven research interest in its peripheral opioid-receptor signaling and its use as a comparative pharmacological reference compound in opioid-receptor binding and selectivity studies.
Dermorphin peptide Scientific Research
Mechanism of Action & Pathways
In experimental models, Dermorphin is studied for its high-affinity interaction with μ-opioid receptors, leading to activation of Gi/Go protein–coupled signaling pathways. These pathways regulate intracellular second messengers such as cyclic AMP and ion channel activity, providing insight into opioid receptor pharmacology and signal transduction dynamics.
Cellular & Molecular Research
Dermorphin is utilized in laboratory studies examining:
- Opioid receptor binding kinetics and selectivity
- GPCR-mediated intracellular signaling cascades
- Peptide stability and resistance to enzymatic degradation
All investigations are conducted in controlled in vitro or biochemical assay environments.
Neurobiology & Peptide Processing Research
Research applications may include:
- Neuropeptide precursor synthesis and processing studies
- Central nervous system signaling models
- Comparative analysis of L- vs. D-amino acid–containing peptides
These studies remain exploratory and mechanistic, without therapeutic interpretation.
Experimental Models
- In vitro receptor-binding and signaling assays
- Ex vivo neural tissue studies
- Non-clinical in vivo preclinical research models
All use is strictly limited to laboratory research contexts.
Article Titles & Journals
Dermorphin tetrapeptide analogs as potent and long-lasting analgesics with pharmacological
Dermorphin-based potential affinity labels for mu-opioid receptors.
The mu-selective heptapeptide opioid dermorphin has two conformations around Phe3 psi with
Pharmacology of amphibian opiate peptides.
The dermaseptin precursors: a protein family with a common preproregion and a variable C-t
Fast, reliable shipping
We offer fast, reliable shipping through UPS and USPS.
Shipping Options
UPS shipping options include:
- Next Day Air
- 2nd Day Air
- 3 Day Select
- UPS Ground
Order Processing
- We ship Monday through Saturday.
- Orders placed before 6:00 PM EST / 3:00 PM PST are typically shipped the same day.
- Orders placed after the daily cutoff or on holidays will be processed on the next available shipping day.
Puerto Rico, Hawaii & Alaska
- Orders shipping to these destinations are sent via USPS unless alternative arrangements have been made in advance.
- Need a different shipping method? Contact us before placing your order so we can discuss available options.
Order Tracking
- Once your order has shipped, you'll receive a shipping confirmation email with tracking information so you can monitor your delivery.
- Orders totaling $200 or more qualify for FREE UPS 2nd Day Air shipping within the continental United States.
- Free 2nd Day Air shipping does not apply to orders shipping to Puerto Rico, Hawaii, or Alaska.
Handled correctly, stability holds
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
Store vials in a cool, dry place away from heat and direct sunlight.
For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Frequently Asked Questions
PRODUCT & PURITY
This product is offered for laboratory and research use only. It is not intended for human consumption, medical use, therapeutic use, or veterinary use.
Yes, all of our products are sterile and sealed with a sterility plug and safety cap.
Our products undergo quality control internally at our lab and then 3rd party tested at Bioviridian (at their Texas facility) prior to shipment. All of our COA's are then posted on our site immediately upon receipt.
99% or higher. Period. The expected purity is listed on the individual product page or Certificate of Analysis, when available.
No. We are a manufacturing company and because these products are sold for research purposes only, we do not provide dosing, administration, or medical-use guidance.
Unless specifically stated otherwise, these products are not approved by the U.S. Food and Drug Administration for therapeutic or diagnostic use.
STORAGE & STABILITY
As a lyophilized powder, peptides are stable. Delays in shipments up to 7 days will have zero to minimal impact on efficacy of peptides. Most precautionary efforts must be made to maintain temperature consistency once reconstituted.
Store the product according to the storage recommendations provided on the label or accompanying documentation in your shipment. Proper storage helps maintain product integrity during its shelf life. Most peptides have an expiration date of 2 years if kept unreconstituted (lyophilized powder).
SHIPPING
Shipping times vary based on your location and the shipping method selected at checkout. We offer shipping options between 1 and 5 days.
No.
Once your order is processed, you will receive a shipping confirmation email with tracking information.
ORDERS
Each order includes the peptide vial as described on the product page above.
We accept all forms of credit cards and Zelle.
If your order has not yet been processed for shipment, we may be able to make changes. Please contact customer support as soon as possible after placing your order.
If your order arrives damaged or incorrect, contact our customer support team promptly at support@peaklabpeptides.com with your order number and photos of the package and product so we can assist you.
For the safety of our researchers and integrity of our products we can not accept returns whatsoever.
SUPPORT
If you have questions about your order or a product, please reach out through our customer support page or contact us at support@peaklabpeptides.com or call/text 605-524-2800.
Purity you can verify
TESTED
VERIFICATION
Peak Lab Peptides maintains quality-control processes and routinely performs third-party testing to support purity and identity verification. COAs are available upon request for applicable batches. Documentation may vary depending on production timelines.
AVAILABILITY
We aim to make batch-level documentation available whenever possible. Our goal is to expand COA access across the full catalog as production capacity grows.
All products are for laboratory research use only and are not intended for human consumption.
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