Ipamorelin
Price range: $26.00 through $35.00
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Description
Ipamorelin
THIS IS NOT FOR HUMAN CONSUMPTION. SOLD FOR RESEARCH ONLY!
Ipamorelin peptide Details
Ipamorelin Certificate of Analysis
Third-party tested. Click image to view full-resolution certificate.
Ipamorelin is a highly selective pentapeptide growth hormone secretagogue that activates the GHSR-1a (ghrelin receptor) without significantly influencing other pituitary hormones. This selectivity makes it ideal for modeling growth hormone (GH) release mechanisms while avoiding off-target effects such as ACTH, prolactin, FSH, LH, TSH, or cortisol modulation.
Ipamorelin triggers Gq/PLC-mediated calcium signaling, leading to GH release from somatotrophs in pituitary tissue. Its receptor-specific action and clean hormonal profile make it a valuable compound for laboratory research into peptide-driven endocrine signaling, metabolic regulation, and musculoskeletal repair models.
About Ipamorelin peptide
- Peptide Type: GH secretagogue analog
- Receptor Target: GHSR-1a (Ghrelin receptor)
- Sequence: Synthetic pentapeptide
- Signaling Pathways: Gq/PLC → Ca²⁺ release; cAMP
- Key Feature: Minimal impact on ACTH, prolactin, cortisol, or gonadotropins
- Use: For in-vitro and in-vivo preclinical research only
5 reviews for Ipamorelin
Ipamorelin peptide Scientific Research
1. Growth Hormone Secretion Modeling
Ipamorelin is used in experimental systems to stimulate GH secretion via GHSR-1a activation. It is employed in studies comparing somatotropic output, receptor selectivity, and pulsatile GH release kinetics with other secretagogues.
2. Receptor–Ligand Binding Assays
The peptide serves as a selective ligand in receptor binding studies to evaluate GHSR-1a affinity, receptor density, and activation thresholds under controlled assay conditions.
3. Endocrine Axis Mapping
Ipamorelin supports mechanistic mapping of the hypothalamic–pituitary–somatotropic (HPS) axis, enabling researchers to dissect GH-specific pathways without affecting adrenal or reproductive hormone cascades.
4. Musculoskeletal Repair Models
In regenerative biology, ipamorelin is used to model peptide-driven tissue growth and repair, including muscle regeneration, tendon healing, and recovery signaling post-injury or stress.
5. Comparative Secretagogue Pharmacology
Frequently studied alongside other GH secretagogues such as GHRP-2, GHRP-6, or hexarelin, ipamorelin enables structure–activity relationship (SAR) evaluations and GH release potency comparisons in vitro.
Ipamorelin peptide FAQ
Q: What is the mechanism of action of Ipamorelin?
A: Ipamorelin binds the GHSR-1a receptor and activates intracellular calcium signaling via the Gq/PLC pathway, leading to growth hormone release.
Q: Does Ipamorelin affect cortisol or prolactin levels?
A: No. Unlike some other GH secretagogues, ipamorelin shows minimal activity on ACTH, cortisol, prolactin, or other pituitary hormones.
Q: What is the main advantage of using Ipamorelin in research?
A: Its high selectivity for GH release allows targeted investigation of GH-related signaling without cross-activation of the adrenal or gonadal axes.
Q: Is Ipamorelin intended for human use?
A: No. Ipamorelin is supplied strictly for laboratory use and not approved for human administration or clinical application.
Q: What type of studies commonly use Ipamorelin?
A: Preclinical studies in endocrinology, receptor pharmacology, tissue regeneration, and metabolic signaling frequently include ipamorelin as a reference compound.
Storage & Handling
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
- On arrival: Store vials in a cool, dry place away from heat and direct sunlight.
- Long-term (powder): For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
- After reconstitution: Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Note: Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Peak Lab Peptides maintains quality-control processes and routinely performs third-party testing to support purity and identity verification. COAs are available upon request for applicable batches. Documentation may vary depending on production timelines.
We aim to make batch-level documentation available whenever possible. Our goal is to expand COA access across the full catalog as production capacity grows.
All products are for laboratory research use only and are not intended for human consumption.
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