HCG

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Purity 99.8% Batch HCG-202604-001 Tested Apr 30, 2026 Full report ↓
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Orders of $5,000 or more
Current batch Passed
Purity 99.8%

99.8% — exceeds 99.00% minimum spec

Batch
HCG-202604-001
Test date
April 30, 2026
Method
HPLC + MS
Lab
Bioviridian
College Station, TX

Description

HCG (Human Chorionic Gonadotropin)

HCG (Human Chorionic Gonadotropin) – 5,000 IU (Lyophilized Powder) – For Research Use Only

Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone naturally produced during pregnancy, commonly studied for its effects on the hypothalamic-pituitary-gonadal (HPG) axis. In research, HCG is used to stimulate testosterone production, luteinizing hormone (LH) activity, and fertility pathways.

HCG is often studied in models exploring spermatogenesis, gonadal function, and hormone regulation in both male and female research subjects.

Product Details:

  • Compound: Human Chorionic Gonadotropin (HCG)

  • Potency: 5,000 IU per vial

  • Form: Lyophilized powder

  • Purity: Research grade

  • Storage: Store at -4°F (-20°C). After reconstitution, refrigerate at 36–46°F (2–8°C) and use within 30 days.

  • Grade: For research purposes only. Not for human consumption, therapeutic, or diagnostic use.

Potential Research Applications:

  • Testosterone stimulation and LH activity studies

  • Fertility and reproductive hormone models

  • Testicular function and spermatogenesis research

  • Endocrine system modulation investigations


For laboratory research use only. This product is not intended to diagnose, treat, cure, or prevent any disease.

THIS IS NOT FOR HUMAN CONSUMPTION. SOLD FOR RESEARCH ONLY!

Description + COA

HCG peptide​ Details

Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone structurally similar to luteinizing hormone (LH), naturally produced by the placenta during pregnancy but studied in reproductive endocrinology for its ability to bind and activate the same LH receptor found in gonadal tissue. In males, this LH-receptor activity stimulates Leydig cells to produce testosterone and supports intratesticular testosterone concentrations important for spermatogenesis, making HCG a frequently studied compound in male reproductive-axis and fertility research, particularly in contexts involving hypothalamic-pituitary-gonadal axis suppression. In females, HCG's LH-receptor activity is central to its established role in ovulation-induction research, where it substitutes for the natural LH surge to trigger final oocyte maturation. HCG's long history of clinical use in reproductive medicine has generated an extensive pharmacological dataset that continues to inform current research into gonadal-axis signaling and fertility-related endocrinology.

Research

HCG peptide​ Scientific Research

  1. HPG Axis and LH Receptor Signaling
    hCG is widely used to study how LH/hCG receptor activation influences gonadal function:
  • Receptor Activation: In cell culture and animal models, hCG exposure activates LH/hCG receptors, allowing researchers to map downstream second messenger systems, such as cAMP-dependent pathways and kinase cascades.
  • Steroidogenesis: hCG stimulation is used to assess the capacity of gonadal cells to synthesize steroids, including testosterone and related intermediates, and to characterize enzyme activity in steroidogenic pathways.
  • Feedback and Regulation: By providing a controlled LH-like stimulus, hCG helps clarify how gonadal hormones feed back on the hypothalamus and pituitary in experimental systems.

These studies support a detailed mechanistic understanding of reproductive hormone signaling and regulation.

  1. Testicular Function and Spermatogenic Support Models
    In testes-focused research, hCG is frequently used as a tool to examine hormone-dependent testicular processes:
  • Leydig Cell Studies: hCG is a standard agonist to study Leydig cell steroidogenesis, receptor density, and signaling adaptation over time.
  • Sertoli and Germ Cell Context: By modulating intratesticular hormone levels in animal models, hCG exposure allows researchers to assess how endocrine signals support spermatogenic environment and germ-cell maturation.
  • Developmental and Functional Assessments: Experimental paradigms sometimes use hCG to explore testicular descent, structural maturation, and hormone responsiveness in developmental models.

These investigations support broader insights into testicular physiology and spermatogenic support mechanisms.

  1. Ovarian and Follicular Research
    Because hCG can act via the same receptor as LH, it is also utilized to model aspects of ovarian function:
  • Follicular Response: In controlled models, hCG exposure is used to study late follicular signaling, luteinization processes, and steroid production.
  • Corpus Luteum Models: hCG serves as an LH surrogate to investigate corpus luteum formation, maintenance, and hormone output.

Such work helps clarify the timing, magnitude, and biochemical consequences of LH-like surges in ovarian physiology.

  1. Endocrine and Signal-Transduction Studies
    hCG is a valuable reagent for dissecting signal-transduction pathways:
  • GPCR Mechanisms: Since the LH/hCG receptor is a G-protein–coupled receptor, hCG is used to explore Gs-mediated cAMP production and downstream kinase activation.
  • Desensitization and Internalization: Repeated or sustained hCG exposure is used to study receptor desensitization, internalization, and recycling, shedding light on hormone-responsiveness dynamics.

These experiments contribute to general GPCR signaling frameworks and receptor pharmacology beyond reproductive biology alone.

  1. Biomarker and Assay Development
    Due to its well-characterized structure and role, hCG also appears in methodological research:
  • Assay Calibration: hCG is frequently used as a standard or calibrator in immunoassays that quantify hormone levels in biological samples.
  • Binding Studies: Radiolabeled or tagged hCG variants are applied to measure receptor binding kinetics, affinity, and receptor density in various tissues or cell lines.

This assay-oriented research underpins many of the measurement techniques used in endocrine and clinical research laboratories.

 

Article Titles & Journals

 

Shipping

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Storage & handling

Handled correctly, stability holds

All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.

01 — ON ARRIVAL

Store vials in a cool, dry place away from heat and direct sunlight.

02 — LONG-TERM (POWDER)

For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.

03 — AFTER RECONSTITUTION

Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.

NOTE

Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.

FAQ

Frequently Asked Questions

PRODUCT & PURITY

This product is offered for laboratory and research use only. It is not intended for human consumption, medical use, therapeutic use, or veterinary use.

Yes, all of our products are sterile and sealed with a sterility plug and safety cap.

Our products undergo quality control internally at our lab and then 3rd party tested at Bioviridian (at their Texas facility) prior to shipment. All of our COA's are then posted on our site immediately upon receipt.

99% or higher. Period. The expected purity is listed on the individual product page or Certificate of Analysis, when available.

No. We are a manufacturing company and because these products are sold for research purposes only, we do not provide dosing, administration, or medical-use guidance.

Unless specifically stated otherwise, these products are not approved by the U.S. Food and Drug Administration for therapeutic or diagnostic use.

STORAGE & STABILITY

As a lyophilized powder, peptides are stable. Delays in shipments up to 7 days will have zero to minimal impact on efficacy of peptides. Most precautionary efforts must be made to maintain temperature consistency once reconstituted.

Store the product according to the storage recommendations provided on the label or accompanying documentation in your shipment. Proper storage helps maintain product integrity during its shelf life. Most peptides have an expiration date of 2 years if kept unreconstituted (lyophilized powder).

SHIPPING

Shipping times vary based on your location and the shipping method selected at checkout. We offer shipping options between 1 and 5 days.

No.

Once your order is processed, you will receive a shipping confirmation email with tracking information.

ORDERS

Each order includes the peptide vial as described on the product page above.

We accept all forms of credit cards and Zelle.

If your order has not yet been processed for shipment, we may be able to make changes. Please contact customer support as soon as possible after placing your order.

If your order arrives damaged or incorrect, contact our customer support team promptly at support@peaklabpeptides.com with your order number and photos of the package and product so we can assist you.

For the safety of our researchers and integrity of our products we can not accept returns whatsoever.

SUPPORT

If you have questions about your order or a product, please reach out through our customer support page or contact us at support@peaklabpeptides.com or call/text 605-524-2800.

QUALITY & TESTING

Purity you can verify

3RD-PARTY
TESTED

VERIFICATION

Peak Lab Peptides maintains quality-control processes and routinely performs third-party testing to support purity and identity verification. COAs are available upon request for applicable batches. Documentation may vary depending on production timelines.

AVAILABILITY

We aim to make batch-level documentation available whenever possible. Our goal is to expand COA access across the full catalog as production capacity grows.

INTENDED USE

All products are for laboratory research use only and are not intended for human consumption.