HGH 191AA
Price range: $50.40 through $99.00
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99.9% — exceeds 99.00% minimum spec
- Batch
- HGH-202604-001
- Test date
- April 30, 2026
- Method
- HPLC + MS
- Lab
-
Bioviridian
College Station, TX
Description
HGH 191AA (Human Growth Hormone, somatropin)
THIS IS NOT FOR HUMAN CONSUMPTION. SOLD FOR RESEARCH ONLY!
HGH 191AA peptide​ Details
HGH 191AA (somatropin) is the 191-amino-acid recombinant form of human growth hormone, structurally identical to the hormone naturally secreted by the anterior pituitary gland's somatotroph cells. As the direct hormone itself — rather than a secretagogue or releasing-hormone analog — it acts on growth hormone receptors throughout the body, most notably in the liver, where it stimulates IGF-1 production, and in adipose and muscle tissue, where it influences lipolysis and protein synthesis directly. HGH 191AA has one of the largest clinical research and pharmaceutical datasets of any hormone in this category, having been studied and approved for decades in the treatment of pediatric and adult growth hormone deficiency. In research contexts, it continues to be studied for its direct effects on body composition, IGF-1 axis signaling, and metabolic parameters, distinguishing it mechanistically from secretagogue peptides (such as Sermorelin, CJC-1295, or Ipamorelin) that work upstream by stimulating the body's own GH release rather than supplying the hormone directly.
HGH 191AA peptide​ Scientific Research
HGH 191AA is frequently used to study the molecular mechanisms of GH receptor activation:
- Receptor Binding: Somatropin binds to GHR on target cells, enabling detailed analysis of receptor affinity, dimerization, and downstream activation.
- Signal Transduction: Experimental designs often track activation of JAK–STAT, PI3K/Akt, and MAPK pathways following Somatropin exposure, helping clarify how GH influences gene expression and cellular behavior.
- Comparative Studies: HGH 191AA serves as a reference compound for comparing native GH activity to analogues, fragments, or modified GH-related molecules.
These studies support a deeper understanding of GH-driven transcriptional programs in liver, muscle, bone, and other tissues.
IGF-1 Regulation and Endocrine Feedback
Somatropin is also used to probe the GH–IGF-1 axis:
- IGF-1 Production: In liver and other IGF-1–producing tissues, Somatropin exposure is used to quantify dose–response relationships between GH stimulation and IGF-1 output.
- Endocrine Loops: Models that manipulate GH and IGF-1 with HGH 191AA help dissect feedback interactions involving growth hormone–releasing hormone (GHRH), somatostatin, and peripheral hormone levels.
This work contributes to endocrine models of growth, metabolism, and systemic signaling.
Metabolism and Tissue Modeling
In controlled research, HGH 191AA may be used to explore how GH signaling interacts with:
- Protein and Lipid Metabolism: Experimental systems can examine shifts in protein turnover, lipid handling, and related enzyme activity when GH pathways are activated.
- Bone and Connective Tissue: Somatropin is applied in models investigating bone formation markers, extracellular matrix regulation, and growth plate biology.
- Body-Composition Frameworks: Animal and in vitro models use GH stimulation to understand how hormone signaling contributes to changes in tissue composition at a mechanistic level, without implying outcomes in humans.
Assay Development and Standardization
Because its structure and activity are well defined, Somatropin is also used in methodological research:
- As a standard in bioassays and immunoassays that quantify GH levels
- As a reference compound in potency, stability, or degradation studies of GH-related products
This supports robust analytical methods in endocrine and pharmacologic research.
Article Titles & Journals
- [Multiple clinical effects of recombinant human growth hormone therapy].
- The combined effect of L-arginine and Vitamin C supplementation on nitrogen balance, body
- Metabolic and bone effects of long-acting polyethylene glycol-recombinant human growth hor
- Overview of Novel Mechanisms in Obesity Pharmacotherapy and Implications for Cardiovascula
- Cardiac and aerobic response to growth hormone therapy in children with short stature: a p
Fast, reliable shipping
We offer fast, reliable shipping through UPS and USPS.
Shipping Options
UPS shipping options include:
- Next Day Air
- 2nd Day Air
- 3 Day Select
- UPS Ground
Order Processing
- We ship Monday through Saturday.
- Orders placed before 6:00 PM EST / 3:00 PM PST are typically shipped the same day.
- Orders placed after the daily cutoff or on holidays will be processed on the next available shipping day.
Puerto Rico, Hawaii & Alaska
- Orders shipping to these destinations are sent via USPS unless alternative arrangements have been made in advance.
- Need a different shipping method? Contact us before placing your order so we can discuss available options.
Order Tracking
- Once your order has shipped, you'll receive a shipping confirmation email with tracking information so you can monitor your delivery.
- Orders totaling $200 or more qualify for FREE UPS 2nd Day Air shipping within the continental United States.
- Free 2nd Day Air shipping does not apply to orders shipping to Puerto Rico, Hawaii, or Alaska.
Handled correctly, stability holds
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
Store vials in a cool, dry place away from heat and direct sunlight.
For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Frequently Asked Questions
PRODUCT & PURITY
This product is offered for laboratory and research use only. It is not intended for human consumption, medical use, therapeutic use, or veterinary use.
Yes, all of our products are sterile and sealed with a sterility plug and safety cap.
Our products undergo quality control internally at our lab and then 3rd party tested at Bioviridian (at their Texas facility) prior to shipment. All of our COA's are then posted on our site immediately upon receipt.
99% or higher. Period. The expected purity is listed on the individual product page or Certificate of Analysis, when available.
No. We are a manufacturing company and because these products are sold for research purposes only, we do not provide dosing, administration, or medical-use guidance.
Unless specifically stated otherwise, these products are not approved by the U.S. Food and Drug Administration for therapeutic or diagnostic use.
STORAGE & STABILITY
As a lyophilized powder, peptides are stable. Delays in shipments up to 7 days will have zero to minimal impact on efficacy of peptides. Most precautionary efforts must be made to maintain temperature consistency once reconstituted.
Store the product according to the storage recommendations provided on the label or accompanying documentation in your shipment. Proper storage helps maintain product integrity during its shelf life. Most peptides have an expiration date of 2 years if kept unreconstituted (lyophilized powder).
SHIPPING
Shipping times vary based on your location and the shipping method selected at checkout. We offer shipping options between 1 and 5 days.
No.
Once your order is processed, you will receive a shipping confirmation email with tracking information.
ORDERS
Each order includes the peptide vial as described on the product page above.
We accept all forms of credit cards and Zelle.
If your order has not yet been processed for shipment, we may be able to make changes. Please contact customer support as soon as possible after placing your order.
If your order arrives damaged or incorrect, contact our customer support team promptly at support@peaklabpeptides.com with your order number and photos of the package and product so we can assist you.
For the safety of our researchers and integrity of our products we can not accept returns whatsoever.
SUPPORT
If you have questions about your order or a product, please reach out through our customer support page or contact us at support@peaklabpeptides.com or call/text 605-524-2800.
Purity you can verify
TESTED
VERIFICATION
Peak Lab Peptides maintains quality-control processes and routinely performs third-party testing to support purity and identity verification. COAs are available upon request for applicable batches. Documentation may vary depending on production timelines.
AVAILABILITY
We aim to make batch-level documentation available whenever possible. Our goal is to expand COA access across the full catalog as production capacity grows.
All products are for laboratory research use only and are not intended for human consumption.
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