HGH Fragment 176-191
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Description
Hgh Fragment 176-191 peptide Details
HGH Fragment 176-191 is the identical C-terminal fragment of human growth hormone that forms the structural basis of AOD-9604, isolated specifically because this region of the hGH molecule retains the hormone's lipolytic (fat-metabolizing) signaling without the growth-promoting or insulin-desensitizing activity associated with the full-length hormone. Research on this fragment has focused on its interaction with adipocyte beta-3 adrenergic receptor signaling, where it is studied for effects on stimulating lipolysis and inhibiting lipogenesis in fat tissue — the same mechanism explored in AOD-9604's clinical-stage development for obesity research. As the foundational fragment behind that clinical candidate, HGH Fragment 176-191 continues to be referenced in fat-metabolism and adipose-tissue signaling research as a tool for studying hGH's lipolytic pathway in isolation from its broader hormonal effects.
Hgh Fragment 176-191 peptide Scientific Research
Mechanism of Action & Pathways
In experimental models, hGH Fragment 176–191 is studied for its ability to activate metabolic signaling cascades without engaging growth hormone or IGF-1 receptors. Research focuses on its interaction with β-adrenergic signaling components and activation of AMPK, a central regulator of cellular energy balance.
Cellular & Metabolic Research
The peptide is utilized in laboratory studies examining:
- Lipid metabolism and fatty acid signaling pathways
- Glucose utilization and intracellular energy flux
- AMPK activation and downstream transcriptional responses
All investigations are conducted in controlled in vitro or biochemical assay environments.
Adipocyte & Energy Regulation Research
Research applications may include:
- Adipocyte differentiation and signaling models
- Energy homeostasis and metabolic adaptation studies
- Peptide-driven modulation of metabolic enzyme activity
These investigations remain exploratory and mechanistic, without therapeutic interpretation.
Experimental Models
- In vitro cellular and enzymatic assays
- Ex vivo metabolic tissue studies
- Non-clinical in vivo preclinical research models
All use is strictly limited to laboratory research contexts.
Article Titles & Journals
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Handled correctly, stability holds
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
Store vials in a cool, dry place away from heat and direct sunlight.
For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Frequently Asked Questions
PRODUCT & PURITY
This product is offered for laboratory and research use only. It is not intended for human consumption, medical use, therapeutic use, or veterinary use.
Yes, all of our products are sterile and sealed with a sterility plug and safety cap.
Our products undergo quality control internally at our lab and then 3rd party tested at Bioviridian (at their Texas facility) prior to shipment. All of our COA's are then posted on our site immediately upon receipt.
99% or higher. Period. The expected purity is listed on the individual product page or Certificate of Analysis, when available.
No. We are a manufacturing company and because these products are sold for research purposes only, we do not provide dosing, administration, or medical-use guidance.
Unless specifically stated otherwise, these products are not approved by the U.S. Food and Drug Administration for therapeutic or diagnostic use.
STORAGE & STABILITY
As a lyophilized powder, peptides are stable. Delays in shipments up to 7 days will have zero to minimal impact on efficacy of peptides. Most precautionary efforts must be made to maintain temperature consistency once reconstituted.
Store the product according to the storage recommendations provided on the label or accompanying documentation in your shipment. Proper storage helps maintain product integrity during its shelf life. Most peptides have an expiration date of 2 years if kept unreconstituted (lyophilized powder).
SHIPPING
Shipping times vary based on your location and the shipping method selected at checkout. We offer shipping options between 1 and 5 days.
No.
Once your order is processed, you will receive a shipping confirmation email with tracking information.
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Each order includes the peptide vial as described on the product page above.
We accept all forms of credit cards and Zelle.
If your order has not yet been processed for shipment, we may be able to make changes. Please contact customer support as soon as possible after placing your order.
If your order arrives damaged or incorrect, contact our customer support team promptly at support@peaklabpeptides.com with your order number and photos of the package and product so we can assist you.
For the safety of our researchers and integrity of our products we can not accept returns whatsoever.
SUPPORT
If you have questions about your order or a product, please reach out through our customer support page or contact us at support@peaklabpeptides.com or call/text 605-524-2800.
Purity you can verify
TESTED
VERIFICATION
Peak Lab Peptides maintains quality-control processes and routinely performs third-party testing to support purity and identity verification. COAs are available upon request for applicable batches. Documentation may vary depending on production timelines.
AVAILABILITY
We aim to make batch-level documentation available whenever possible. Our goal is to expand COA access across the full catalog as production capacity grows.
All products are for laboratory research use only and are not intended for human consumption.
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- Form: Lyophilized powder
- Purity: >99%
- Quantity: 80mg vial
- Storage: Store at -4°F (-20°C). After reconstitution, refrigerate at 36–46°F (2–8°C) and use within 30 days.
- Grade: For research purposes only. Not for human consumption, therapeutic, or diagnostic use.
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Lifetime Value Comparison
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- Purity: >98%
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- Storage: Store at -4°F (-20°C). After reconstitution, refrigerate at 36–46°F (2–8°C) and use within 30 days.
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All materials are strictly for laboratory research purposes.
Not for human consumption.