HGH Fragment 176-191
Price range: $27.80 through $64.80
Become a Member and save 20% on Every Order.
Description
Hgh Fragment 176-191 peptide Details
hGH Fragment 176–191 is a synthetic research peptide corresponding to a specific C-terminal region of the human growth hormone (hGH) sequence, comprising amino acids 177–191. In laboratory research settings, this peptide fragment is studied for its role in metabolic signaling pathways that are distinct from classical growth hormone receptor and IGF-1 receptor activation.
Experimental studies indicate that hGH Fragment 176–191 modulates lipid and glucose metabolism through β-adrenergic–associated signaling and AMP-activated protein kinase (AMPK)–mediated pathways in controlled in vitro and preclinical models. Due to its receptor-independent signaling profile, this fragment serves as a useful molecular tool for examining energy regulation and metabolic peptide function without engaging canonical somatotropic growth pathways.
hGH Fragment 176–191 is supplied exclusively for scientific and laboratory research use. It is not intended for human or veterinary consumption, clinical investigation, diagnostic use, or therapeutic application.
About Hgh Fragment 176-191 peptide
Chemical Identity & Classification
- Synthetic peptide fragment derived from human growth hormone
- Sequence region: amino acids 177–191
- Metabolic signaling research compound
Why Researchers Study hGH Fragment 176–191
- To investigate lipid metabolism signaling independent of IGF-1
- To study AMPK-mediated energy regulation pathways
- To explore β-adrenergic signaling effects in metabolic research models
Key Research Systems & Pathways
- β-adrenergic–associated signaling networks
- AMPK-dependent energy sensing pathways
- Adipocyte signaling and metabolic regulation
- Peptide-mediated modulation of glucose and lipid handling
The peptide is synthesized under controlled laboratory conditions to ensure high purity, molecular accuracy, and reproducibility for preclinical research applications.
Hgh Fragment 176-191 peptide Scientific Research
Mechanism of Action & Pathways
In experimental models, hGH Fragment 176–191 is studied for its ability to activate metabolic signaling cascades without engaging growth hormone or IGF-1 receptors. Research focuses on its interaction with β-adrenergic signaling components and activation of AMPK, a central regulator of cellular energy balance.
Cellular & Metabolic Research
The peptide is utilized in laboratory studies examining:
- Lipid metabolism and fatty acid signaling pathways
- Glucose utilization and intracellular energy flux
- AMPK activation and downstream transcriptional responses
All investigations are conducted in controlled in vitro or biochemical assay environments.
Adipocyte & Energy Regulation Research
Research applications may include:
- Adipocyte differentiation and signaling models
- Energy homeostasis and metabolic adaptation studies
- Peptide-driven modulation of metabolic enzyme activity
These investigations remain exploratory and mechanistic, without therapeutic interpretation.
Experimental Models
- In vitro cellular and enzymatic assays
- Ex vivo metabolic tissue studies
- Non-clinical in vivo preclinical research models
All use is strictly limited to laboratory research contexts.
Hgh Fragment 176-191 peptide FAQ
What is hGH Fragment 176–191 used for in research?
It is used in laboratory research to study metabolic signaling pathways related to lipid and glucose regulation independent of IGF-1 receptor activation.
What makes this fragment different from full-length growth hormone?
Unlike full-length growth hormone, this fragment does not activate classical GH or IGF-1 receptors and is studied specifically for its metabolic signaling effects.
Which pathways are most commonly studied with this peptide?
Research focuses on β-adrenergic signaling and AMPK-mediated energy regulation pathways.
Is hGH Fragment 176–191 approved for human or clinical use?
No. This peptide is strictly for research use only and is not intended for human consumption, veterinary use, or clinical application.
How should hGH Fragment 176–191 be stored and handled?
It should be stored and handled according to standard laboratory peptide storage and handling practices to preserve stability and integrity.
Storage & Handling
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
- On arrival: Store vials in a cool, dry place away from heat and direct sunlight.
- Long-term (powder): For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
- After reconstitution: Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Note: Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Peak Lab Peptides maintains quality-control processes and routinely performs third-party testing to support purity and identity verification. COAs are available upon request for applicable batches. Documentation may vary depending on production timelines.
We aim to make batch-level documentation available whenever possible. Our goal is to expand COA access across the full catalog as production capacity grows.
All products are for laboratory research use only and are not intended for human consumption.
Related Products
IGF-1 LR3
IGF-1 LR3 Peptide
IGF-1 LR3 Peptide (Long Arg3 Insulin-Like Growth Factor-1) – 1mg (Lyophilized Peptide) – For Research Use Only
IGF-1 LR3 is a synthetic analog of human Insulin-Like Growth Factor-1 (IGF-1), modified to extend its half-life in vitro through substitution of arginine at position 3 and removal of the first three amino acids of the native IGF-1 sequence. These modifications increase resistance to IGF-1 binding proteins, enhancing stability and prolonged activity in controlled research environments. Research has explored its role in cellular growth signaling, differentiation pathways, and IGF-1 receptor interaction mechanisms in laboratory models.
Product Details:
- Peptide: IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1)
- Sequence: 83 amino acids
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Quantity: 1mg per vial
- Storage: Store lyophilized peptide at -4°F (-20°C). Once reconstituted, refrigerate at 36–46°F (2–8°C) and use within 30 days.
- Grade: For laboratory research use only. Not for human use, consumption, or therapeutic applications.
Potential Research Applications:
- IGF-1 receptor binding affinity and cellular signaling studies
- Cellular growth and differentiation pathway research
- Binding protein resistance and in vitro stability mechanism models
- Growth factor analog activity and structure-function investigations
For laboratory research only. This product is not intended to diagnose, treat, cure, or prevent any disease.
KLOW Blend 80mg – GHK-Cu, TB-500, BPC-157, KPV
KLOW Blend
KLOW – 80mg Peptide Blend (Lyophilized Powder) – For Research Use Only GHK-Cu • TB-500 • BPC-157 • KPV
KLOW is an advanced 4-in-1 research peptide blend combining 80mg of compounds studied for their potential in tissue repair signaling, immune modulation, and cellular recovery mechanisms in controlled laboratory environments. Each component contributes a distinct and complementary mechanism of action, making KLOW a subject of interest in multi-pathway research models.
Active Ingredients (Per Vial):
GHK-Cu – 50mg A copper-binding tripeptide studied for its role in collagen synthesis, cellular regeneration signaling, and extracellular matrix remodeling in laboratory research models.
TB-500 – 10mg A synthetic fragment of Thymosin Beta-4 studied for its interaction with G-actin sequestration, angiogenesis pathway activity, and cell migration mechanisms in preclinical research.
BPC-157 – 10mg A synthetic pentadecapeptide derived from a gastric protein, studied for its role in tissue repair signaling, NO system modulation, and VEGF pathway activity in controlled research environments.
KPV – 10mg A naturally occurring tripeptide fragment studied for its role in inflammatory signaling pathway modulation and immune regulation mechanisms across multiple tissue types.
Product Details:
- Total Peptide Content: 80mg per vial
- Form: Lyophilized powder
- Purity: >99%
- Quantity: 80mg vial
- Storage: Store at -4°F (-20°C). After reconstitution, refrigerate at 36–46°F (2–8°C) and use within 30 days.
- Grade: For research purposes only. Not for human consumption, therapeutic, or diagnostic use.
Potential Research Applications:
- Multi-peptide synergy and complementary pathway mechanism studies
- Cellular regeneration signaling and extracellular matrix research
- Inflammatory pathway modulation and immune regulation models
- Angiogenesis, cell migration, and tissue repair signaling investigations
For laboratory research only. This product is not intended to diagnose, treat, cure, or prevent any disease.
KPV (Lysine-Proline-Valine)
KPV
KPV – 10mg (Lyophilized Peptide) – For Research Use Only
KPV (Lys-Pro-Val) is a naturally occurring tripeptide derived from the C-terminal end of alpha-melanocyte-stimulating hormone (α-MSH), studied for its potential to modulate inflammatory signaling pathways and immune regulation in controlled laboratory environments. Research has explored its activity in epithelial barrier function, cytokine modulation, and localized inflammatory response mechanisms across multiple tissue types.
Product Details:
- Peptide: KPV (Lys-Pro-Val)
- Purity: >99%
- Form: Lyophilized powder
- Quantity: 10mg per vial
- Storage: Store at -4°F (-20°C). After reconstitution, refrigerate at 36–46°F (2–8°C) and use within 30 days.
- Grade: For research purposes only. Not for human consumption, therapeutic, or diagnostic use.
Potential Research Applications:
- Inflammatory signaling pathway modulation studies
- Epithelial barrier function and mucosal tissue research
- Cytokine regulation and immune response mechanism models
- α-MSH derived peptide activity and receptor interaction investigations
For laboratory research only. This product is not intended to diagnose, treat, cure, or prevent any disease.
