IGF-DES 2mg
Original price was: $95.00.$77.00Current price is: $77.00.
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Description
IGF DES peptide 2 mg Details
IGF-1 DES (Des(1-3)IGF-1) is a truncated analog of insulin-like growth factor-1 missing the first three N-terminal amino acids, a modification that substantially reduces its binding affinity to IGF-binding proteins (IGFBPs) — the plasma proteins that normally sequester and regulate circulating IGF-1 activity. Similar in rationale to IGF-1 LR3, this reduced IGFBP affinity is Des-IGF-1's defining research property: because native IGF-1 is heavily buffered by IGFBPs, removing this regulatory binding allows researchers to study more sustained, unbuffered IGF-1 receptor activation. Published research has examined Des-IGF-1's potency at the IGF-1 receptor relative to standard IGF-1, often reporting significantly enhanced biological activity in cell-based assays due to this reduced buffering, making it a frequently used tool compound in IGF-1 receptor signaling and muscle-cell proliferation research.
IGF DES peptide 2 mg Scientific Research
1. Muscle Hypertrophy & Protein Synthesis
IGF-DES is commonly used in studies focused on skeletal muscle growth and localized hypertrophy, due to its enhanced activity in muscle tissue. It stimulates myoblast proliferation, satellite cell activation, and mTOR signaling pathways, contributing to muscle fiber development in preclinical models.
2. Tissue Regeneration & Injury Recovery
This peptide analog plays a key role in wound healing, ligament repair, and post-injury muscle recovery studies. Researchers investigate IGF-DES’s ability to enhance fibroblast proliferation, collagen expression, and structural tissue reformation.
3. Reduced IGFBP Affinity = Enhanced Bioactivity
By lacking the first three amino acids of IGF-1, IGF-DES exhibits lower affinity to insulin-like growth factor binding proteins, allowing more free peptide to interact with IGF-1 receptors in localized tissues.
4. Pharmacokinetics & Delivery Optimization
Studies frequently examine administration routes (e.g., localized intramuscular injection) and timing protocols to optimize retention, distribution, and receptor activation within target tissues in animal models.
Article Titles & Journals
- Necdin-E2F4 interaction provides insulin-sensitizing effect after weight loss induced by g
- Functional characterization of des-IGF-1 action at excitatory synapses in the CA1 region o
- Insulin-like growth factor-1 downregulates nuclear factor kappa B activation and upregulat
- Differential effects of des IGF-1 on Erks, AKT-1 and P70 S6K activation in mouse skeletal
- Regulation of myeloid growth and differentiation by the insulin-like growth factor I recep
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- Free 2nd Day Air shipping does not apply to orders shipping to Puerto Rico, Hawaii, or Alaska.
Handled correctly, stability holds
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
Store vials in a cool, dry place away from heat and direct sunlight.
For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Frequently Asked Questions
PRODUCT & PURITY
This product is offered for laboratory and research use only. It is not intended for human consumption, medical use, therapeutic use, or veterinary use.
Yes, all of our products are sterile and sealed with a sterility plug and safety cap.
Our products undergo quality control internally at our lab and then 3rd party tested at Bioviridian (at their Texas facility) prior to shipment. All of our COA's are then posted on our site immediately upon receipt.
99% or higher. Period. The expected purity is listed on the individual product page or Certificate of Analysis, when available.
No. We are a manufacturing company and because these products are sold for research purposes only, we do not provide dosing, administration, or medical-use guidance.
Unless specifically stated otherwise, these products are not approved by the U.S. Food and Drug Administration for therapeutic or diagnostic use.
STORAGE & STABILITY
As a lyophilized powder, peptides are stable. Delays in shipments up to 7 days will have zero to minimal impact on efficacy of peptides. Most precautionary efforts must be made to maintain temperature consistency once reconstituted.
Store the product according to the storage recommendations provided on the label or accompanying documentation in your shipment. Proper storage helps maintain product integrity during its shelf life. Most peptides have an expiration date of 2 years if kept unreconstituted (lyophilized powder).
SHIPPING
Shipping times vary based on your location and the shipping method selected at checkout. We offer shipping options between 1 and 5 days.
No.
Once your order is processed, you will receive a shipping confirmation email with tracking information.
ORDERS
Each order includes the peptide vial as described on the product page above.
We accept all forms of credit cards and Zelle.
If your order has not yet been processed for shipment, we may be able to make changes. Please contact customer support as soon as possible after placing your order.
If your order arrives damaged or incorrect, contact our customer support team promptly at support@peaklabpeptides.com with your order number and photos of the package and product so we can assist you.
For the safety of our researchers and integrity of our products we can not accept returns whatsoever.
SUPPORT
If you have questions about your order or a product, please reach out through our customer support page or contact us at support@peaklabpeptides.com or call/text 605-524-2800.
Purity you can verify
TESTED
VERIFICATION
Peak Lab Peptides maintains quality-control processes and routinely performs third-party testing to support purity and identity verification. COAs are available upon request for applicable batches. Documentation may vary depending on production timelines.
AVAILABILITY
We aim to make batch-level documentation available whenever possible. Our goal is to expand COA access across the full catalog as production capacity grows.
All products are for laboratory research use only and are not intended for human consumption.
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