HMG (75iu)
Original price was: $50.50.$41.00Current price is: $41.00.
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99.8% — exceeds 99.00% minimum spec
- Batch
- MG-202604-001
- Test date
- April 30, 2026
- Method
- HPLC + MS
- Lab
-
Bioviridian
College Station, TX
Description
HMG (Human Menopausal Gonadotropin)| HMG Peptide 75iu
THIS IS NOT FOR HUMAN CONSUMPTION. SOLD FOR RESEARCH ONLY!
HMG Peptide 75iu Details
Human Menopausal Gonadotropin (HMG) is a purified preparation containing both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity, originally extracted from the urine of postmenopausal women, whose elevated gonadotropin levels (due to loss of negative feedback from declining ovarian hormone production) make it a natural source of these pituitary hormones. HMG's combined FSH/LH activity is the basis of its long-standing use in reproductive endocrinology research, where it is studied for its ability to stimulate follicular development and gonadal steroidogenesis in ways that FSH-only preparations cannot fully replicate, since LH activity supports thecal-cell androgen production feeding into the follicular estrogen-synthesis pathway. Research applications include studies of ovarian stimulation protocols, male gonadal function, and the broader physiology of the hypothalamic-pituitary-gonadal axis under exogenous gonadotropin stimulation.
HMG Peptide 75iu Scientific Research
Gonadotropin Biology and Ovarian Models
HMG 75 IU/vial is frequently used to investigate FSH- and LH-mediated events in ovarian tissue:
- Follicle Development: The FSH component is used to induce an increase in the number of growing follicles and to study dose–response relationships in follicular recruitment and maturation.
- Granulosa and Theca Cell Interactions:
- FSH is applied to granulosa cells to examine estradiol biosynthesis.
- LH is used to stimulate theca cells to produce androgens that can be aromatized to estrogens under FSH influence.
- Steroidogenesis Pathways: By adjusting the relative contribution of FSH and LH activity, researchers can dissect enzymatic steps and regulatory loops in ovarian steroid production.
These models are useful for characterizing follicular dynamics and hormone production without making clinical claims regarding ovulation induction or treatment outcomes.
Testicular and Sertoli Cell Research
In testicular research, HMG 75 IU/vial provides an experimental tool for studying FSH-dependent processes:
- Sertoli Cell Maturation: FSH is used to explore the transformation of premature into mature Sertoli cells and to assess how these cells support germ-cell development within the seminiferous tubules.
- Seminiferous Tubule Development: HMG exposure allows investigators to monitor structural and functional changes in seminiferous canals under defined endocrine conditions.
- Spermatogenic Environment: When combined with appropriate intratesticular androgen environments (e.g., modeled via separate hCG exposure in research), HMG can be used to examine how FSH/LH activity shapes the milieu necessary for sperm development.
Such work is carried out purely for mechanistic insight and is not equivalent to clinical protocols in humans.
Pharmacokinetic Properties in Experimental Systems
Product-specific pharmacokinetic evaluations provide the following general characteristics for the FSH component of HMG 75 IU/vial in research models:
- Route of Administration: Not effective orally; used via intramuscular (i.m.) or subcutaneous (s.c.) injection in experimental settings.
- Time to Peak (Tmax):
- 6–48 hours after i.m. administration
- 6–36 hours after s.c. administration
- Half-Life:
- ~56 hours following i.m. injection
- ~51 hours following s.c. injection
- Elimination: Predominantly renal excretion of administered gonadotropin fractions.
These parameters help researchers design dosing schedules, sampling schemes, and kinetic models when examining gonadotropin exposure and downstream endocrine responses.
Steroidogenic and Gametotropic Effects (Research Context)
In aggregate, the combined FSH/LH action of HMG 75 IU/vial is used to model:
- Gametotropic Effects: Follicular development in the ovary and Sertoli cell–mediated support of spermatogenesis in the testes.
- Steroidogenic Effects: Androgen and estrogen production via granulosa–theca and Leydig–Sertoli cell interactions, enabling detailed study of enzyme regulation and feedback within the hypothalamic–pituitary–gonadal axis.
All such effects are investigated strictly within controlled preclinical or in vitro frameworks.
Article Titles & Journals
- Medroxyprogesterone acetate vs. GnRH antagonist for preventing premature LH surge during o
- Optimizing mature oocyte yield in IVF: clinical comparison of r-hFSH+r-hLH and HMG in wome
- A Decade With Sheehan's Syndrome: A Case Report and Personal Experience.
- Does HCG and LH supplementation during ovarian stimulation improve clinical outcome? An ev
- FSH/LH co-stimulation in Advanced Maternal Age (AMA) and hypo-responder patients - Arabian
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Order Processing
- We ship Monday through Saturday.
- Orders placed before 6:00 PM EST / 3:00 PM PST are typically shipped the same day.
- Orders placed after the daily cutoff or on holidays will be processed on the next available shipping day.
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Order Tracking
- Once your order has shipped, you'll receive a shipping confirmation email with tracking information so you can monitor your delivery.
- Orders totaling $200 or more qualify for FREE UPS 2nd Day Air shipping within the continental United States.
- Free 2nd Day Air shipping does not apply to orders shipping to Puerto Rico, Hawaii, or Alaska.
Handled correctly, stability holds
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
Store vials in a cool, dry place away from heat and direct sunlight.
For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Frequently Asked Questions
PRODUCT & PURITY
This product is offered for laboratory and research use only. It is not intended for human consumption, medical use, therapeutic use, or veterinary use.
Yes, all of our products are sterile and sealed with a sterility plug and safety cap.
Our products undergo quality control internally at our lab and then 3rd party tested at Bioviridian (at their Texas facility) prior to shipment. All of our COA's are then posted on our site immediately upon receipt.
99% or higher. Period. The expected purity is listed on the individual product page or Certificate of Analysis, when available.
No. We are a manufacturing company and because these products are sold for research purposes only, we do not provide dosing, administration, or medical-use guidance.
Unless specifically stated otherwise, these products are not approved by the U.S. Food and Drug Administration for therapeutic or diagnostic use.
STORAGE & STABILITY
As a lyophilized powder, peptides are stable. Delays in shipments up to 7 days will have zero to minimal impact on efficacy of peptides. Most precautionary efforts must be made to maintain temperature consistency once reconstituted.
Store the product according to the storage recommendations provided on the label or accompanying documentation in your shipment. Proper storage helps maintain product integrity during its shelf life. Most peptides have an expiration date of 2 years if kept unreconstituted (lyophilized powder).
SHIPPING
Shipping times vary based on your location and the shipping method selected at checkout. We offer shipping options between 1 and 5 days.
No.
Once your order is processed, you will receive a shipping confirmation email with tracking information.
ORDERS
Each order includes the peptide vial as described on the product page above.
We accept all forms of credit cards and Zelle.
If your order has not yet been processed for shipment, we may be able to make changes. Please contact customer support as soon as possible after placing your order.
If your order arrives damaged or incorrect, contact our customer support team promptly at support@peaklabpeptides.com with your order number and photos of the package and product so we can assist you.
For the safety of our researchers and integrity of our products we can not accept returns whatsoever.
SUPPORT
If you have questions about your order or a product, please reach out through our customer support page or contact us at support@peaklabpeptides.com or call/text 605-524-2800.
Purity you can verify
TESTED
VERIFICATION
Peak Lab Peptides maintains quality-control processes and routinely performs third-party testing to support purity and identity verification. COAs are available upon request for applicable batches. Documentation may vary depending on production timelines.
AVAILABILITY
We aim to make batch-level documentation available whenever possible. Our goal is to expand COA access across the full catalog as production capacity grows.
All products are for laboratory research use only and are not intended for human consumption.
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