KissPeptin-10
Price range: $30.00 through $34.00
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Description
Kisspeptin-10
THIS IS NOT FOR HUMAN CONSUMPTION. SOLD FOR RESEARCH ONLY!
Kisspeptin 10 Peptide Details
Kisspeptin-10 is a synthetic decapeptide (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂) that corresponds to the active C-terminal fragment of the KISS1 gene product. It binds selectively to the KISS1R (GPR54) receptor and activates Gq-mediated intracellular signaling, including calcium mobilization and kinase cascades.
This peptide is widely used in experimental systems investigating hypothalamic–pituitary–gonadal axis regulation, reproductive peptide pathways, metabolic signaling, and cellular adhesion mechanisms. Kisspeptin-10 is offered as a high-purity lyophilized peptide strictly for laboratory and preclinical research.
About Kisspeptin 10 Peptide
- Peptide Type: Synthetic decapeptide
- Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
- Receptor Target: KISS1R / GPR54
- Primary Functions: GnRH stimulation, reproductive axis signaling, metabolic regulation
- Format: Lyophilized peptide, 10mg vial
- Purity: ≥99% (HPLC-verified)
- Usage: Research-only (not for human use)
Kisspeptin 10 Peptide Scientific Research
1. GnRH Neuron Activation & Gonadotropin Dynamics
Kisspeptin-10 is a standard tool in studies evaluating how KISS1R activation modulates GnRH neuronal excitability and pulsatile luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release. This helps elucidate reproductive feedback mechanisms and hormonal regulation in preclinical models.
2. Energy Balance & Metabolic Signaling
Kisspeptin neurons function as integrators of metabolic state and reproductive signals. Animal studies show kisspeptin’s role in adipose signaling, energy expenditure, and body weight regulation, especially through KISS1R expressed in peripheral tissues.
3. Cancer Cell Migration & Tumor Biology
Kisspeptin signaling is researched for its role in tumor cell motility, invasion, and adhesion. It is particularly relevant in metastasis studies across breast, melanoma, and reproductive cancer models due to its pathway interaction with cytoskeletal and adhesion proteins.
4. Cognitive & Behavioral Paradigms
Rodent models have used kisspeptin-10 analogs to study its impact on learning, memory, spatial navigation, and affective behaviors. These effects are linked to kisspeptin’s modulation of limbic circuits and neuropeptide receptor expression in cognition-relevant regions.
5. Renal & Cardiovascular Research
KISS1R is expressed in kidneys and vascular tissues. Research models examine its influence on renal development, vascular tone, and tissue-specific receptor functions, contributing to exploratory work on peptide signaling in circulatory and excretory systems.
Kisspeptin 10 Peptide FAQ
Q: What is Kisspeptin-10 primarily used for in research?
A: It is used to explore reproductive hormone regulation, GnRH neuron signaling, tumor migration, metabolic pathways, and neurobehavioral functions.
Q: How does Kisspeptin-10 differ from full-length kisspeptin?
A: Kisspeptin-10 is the most bioactive core fragment and binds to KISS1R with high potency, making it suitable for targeted receptor studies with minimized sequence complexity.
Q: Is Kisspeptin-10 safe for human use?
A: No. This peptide is intended strictly for laboratory research and is not approved for therapeutic or diagnostic use in humans.
Q: Can it be used in fertility or weight loss applications?
A: While animal models suggest relevance in reproductive and metabolic pathways, it is not authorized for any clinical application outside controlled research.
Q: How should Kisspeptin-10 be stored?
A: Store the lyophilized vial at -20°C. After reconstitution, refrigerate and use within a few days under sterile conditions.
Storage & Handling
All peptides are supplied as sterile, lyophilized powder and are stable when handled correctly.
- On arrival: Store vials in a cool, dry place away from heat and direct sunlight.
- Long-term (powder): For optimal longevity, keep lyophilized peptides refrigerated to help maintain integrity.
- After reconstitution: Use an appropriate research diluent (for example, BAC water). Store the reconstituted solution in the refrigerator and use within 20–30 days for best stability.
Note: Minimize exposure to moisture and repeated freeze–thaw cycles. Follow your institution's safety procedures when handling research materials.
Peak Lab Peptides maintains quality-control processes and routinely performs third-party testing to support purity and identity verification. COAs are available upon request for applicable batches. Documentation may vary depending on production timelines.
We aim to make batch-level documentation available whenever possible. Our goal is to expand COA access across the full catalog as production capacity grows.
All products are for laboratory research use only and are not intended for human consumption.
